Torna ai risultati della ricercaBando per assegno di ricerca
| Titolo del progetto di ricerca in italiano | Studi strutturali sui componenti del flagello di Helicobacter pylori |
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| Titolo del progetto di ricerca in inglese | Structural studies of components of Helicobacter pylori flagellum |
| Settore Concorsuale | 05 - Scienze biologiche |
| S.S.D | - |
| Descrizione sintetica in italiano | For this specific project the objective is the determination of the structure of three flagellar proteins, two FlgE's and one FlgK, and possibly the complex among them. In parallel, we will try to Obtain the structure of the assembly of the organization of FlgE in the filament by cryo-EM, similarly to the case of Salmonella sp. FlgE. In H. pylori, two genes, both coding for FlgE, are present: HP0908 and HP0870. The crystal structure of HP0908, Whose data are Already available, will be refined and completed. FlgK. FlgK from H. pylori (HP1119) has Already Been Expressed. Despite it presents some problems of stability, attempts to grow crystals will be performed. In Additions, FlgL will be cloned and Expressed in order to test The Possibility of growing crystals of the complex. Finally, EM studies of complexes or aggregates of FlgE and FlgK and FlgL will be performed |
| Descrizione sintetica in inglese | For this specific project the objective is the determination of the structure of three flagellar proteins, two FlgE's and one FlgK, and possibly the complex among them. In parallel, we will try to Obtain the structure of the assembly of the organization of FlgE in the filament by cryo-EM, similarly to the case of Salmonella sp. FlgE. In H. pylori, two genes, both coding for FlgE, are present: HP0908 and HP0870. The crystal structure of HP0908, Whose data are Already available, will be refined and completed. FlgK. FlgK from H. pylori (HP1119) has Already Been Expressed. Despite it presents some problems of stability, attempts to grow crystals will be performed. In Additions, FlgL will be cloned and Expressed in order to test The Possibility of growing crystals of the complex. Finally, EM studies of complexes or aggregates of FlgE and FlgK and FlgL will be performed |
| Data del bando | 11/11/2016 |
| Paesi in cui può essere condotta la ricerca |
Italy |
| Paesi di residenza dei candidati |
OTHER |
| Nazionalità dei candidati |
OTHER |
| Sito web del bando | http://www.biomed.unipd.it/ |
| Destinatari dell'assegno di ricerca (of target group) |
Early stage researcher or 0-4 yrs (Post graduate) |
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| Nome dell'Ente finanziatore | Università degli Studi di Padova |
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| Tipologia dell'Ente | Public research |
| Paese dell'Ente | Italy |
| Città | Padova |
| Sito web | http://www.biomed.unipd.it/ |
| giuseppe.zanotti@unipd.it |
| L'assegno finanziato/cofinanziato attraverso un EU Research Framework Programme? | No |
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| Data di scadenza del bando | 05/12/2016 |
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| Come candidarsi | Other |