Torna ai risultati della ricercaBando per assegno di ricerca
| Titolo del progetto di ricerca in italiano | Caratterizzazione di un nuovo gene coinvolto nella farmaco-resistenza ai chemioterapici e suo uso come indicatore diagnostico/prognostico e per la terapia dei carcinomi solidi |
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| Titolo del progetto di ricerca in inglese | Characterization of variant-BTK, a novel gene responsible for resistance to chemotherapy and its usage as diagnostic/prognostic marker and for the therapy of solid cancers |
| Campo principale della ricerca | Medical sciences |
| Sottocampo della ricerca | Medicine |
| Settore Concorsuale | 06 - Scienze mediche |
| S.S.D | MED/04 - PATOLOGIA GENERALE |
| Descrizione sintetica in italiano | Using a specific BTK* antibody a retrospective study will be carried out by TMA on 2 groups: 1) colon carcinoma samples at different stages, in order to establish whether BTK* expression is an early rather than a late tumorigenesis marker. 2) colon carcinoma samples from chemotherapy resistant vs responsive patients, as inferred from their clinical history. For resistant patients, when possible, tumoral samples from surgery or biopsy collected before therapy and at the relapse will be analysed. This kind of analysis will define whether BTK* expression can predict tumor responsivity to chemotherapy. All the samples for the retrospective study will be obtained from collections of paraffin blocks already existent in the Pahology sections of several Hospitals already collaborating with us. |
| Descrizione sintetica in inglese | http://www.unimib.it/link/news.jsp?4120735391417396767 Using a specific BTK* antibody a retrospective study will be carried out by TMA on 2 groups: 1) colon carcinoma samples at different stages, in order to establish whether BTK* expression is an early rather than a late tumorigenesis marker. 2) colon carcinoma samples from chemotherapy resistant vs responsive patients, as inferred from their clinical history. For resistant patients, when possible, tumoral samples from surgery or biopsy collected before therapy and at the relapse will be analysed. This kind of analysis will define whether BTK* expression can predict tumor responsivity to chemotherapy. All the samples for the retrospective study will be obtained from collections of paraffin blocks already existent in the Pahology sections of several Hospitals already collaborating with us. |
| Data del bando | 23/11/2011 |
| Paesi in cui può essere condotta la ricerca |
Italy |
| Paesi di residenza dei candidati |
All |
| Nazionalità dei candidati |
All |
| Sito web del bando | http://www.unimib.it/link/news.jsp?4120735391417396767 |
| Destinatari dell'assegno di ricerca (of target group) |
Early stage researcher or 0-4 yrs (Post graduate) Experienced researcher or 4-10 yrs (Post-Doc) |
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| Nome dell'Ente finanziatore | Regione Lombardia |
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| Tipologia dell'Ente | Public research |
| Paese dell'Ente | Italy |
| Città | Milano |
| Sito web | http://www.unimib.it |
| bandi.assegni_borse@unimib.it |
| L'assegno finanziato/cofinanziato attraverso un EU Research Framework Programme? | No |
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| Data di scadenza del bando | 12/12/2011 - alle ore 00:00 |
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