Descrizione del bando

Titolo del progetto di ricerca in italiano	Announcement of competition for a PhD position (ETN) Marie Skłodowska-Curie (MSCA ITN) entitle “NEUROtransmitter TRANSporters: From single molecules to human pathologies” funded by the European Commission (Grant agreement no: 860954)
Titolo del progetto di ricerca in inglese	Announcement of competition for a PhD position (ETN) Marie Skłodowska-Curie (MSCA ITN) entitle “NEUROtransmitter TRANSporters: From single molecules to human pathologies” funded by the European Commission (Grant agreement no: 860954)
Settore Concorsuale	06 - Scienze mediche
S.S.D	-
Descrizione sintetica in italiano	Electrophysiological approaches to study, ion coupling and transport by NSS. The aim of this project is to comprehend how sodium electrochemical gradient energizes the translocation of the substrates in the various steps of the cycle of GABA transporters. The sodium ions and substrates interaction in each step will be investigated by examining with electrophysiological approaches the currents (pre-steady state, leakage and steady-state currents) recorded in different conditions.The biophysical data will be integrated with the uptake data: acquiring, in the same experiments, in a radiolabelled free approach. This study will help to develop a complete model of the transport cycle in the presence of the substrate and of the inhibitors. Wild type, mutants, and chimeric GABA transporters will be analyzed. for more information see (https://www.neurotrans.org/projects/project-6-electrophysiological-approaches-to-study-ion-coupling-and-transport-by-nss/)
Descrizione sintetica in inglese	Electrophysiological approaches to study, ion coupling and transport by NSS. The aim of this project is to comprehend how sodium electrochemical gradient energizes the translocation of the substrates in the various steps of the cycle of GABA transporters. The sodium ions and substrates interaction in each step will be investigated by examining with electrophysiological approaches the currents (pre-steady state, leakage and steady-state currents) recorded in different conditions.The biophysical data will be integrated with the uptake data: acquiring, in the same experiments, in a radiolabelled free approach. This study will help to develop a complete model of the transport cycle in the presence of the substrate and of the inhibitors. Wild type, mutants, and chimeric GABA transporters will be analyzed. for more information see (https://www.neurotrans.org/projects/project-6-electrophysiological-approaches-to-study-ion-coupling-and-transport-by-nss/)
Data del bando	18/05/2020
Numero di assegnazioni per anno	1
E' richiesta mobilità internazionale?	yes
Paesi in cui può essere condotta la ricerca	Italy
Paesi di residenza dei candidati	OTHER
Nazionalità dei candidati	OTHER
Sito web del bando	https://www.uninsubria.it/la-didattica/dottorati-di-ricerca

 

Dettagli della borsa per dottorato

Destinatari della borsa di ricerca (of target group)	Early stage researcher or 0-4 yrs (Post graduate)
Criteri di selezione in italiano (breve descrizione)	The application for admission to PhD studies shall be submitted by the deadline 22 june 2020, 12 pm (CET). Applicants should consult the webpage of NeuroTrans (www.neurotrans.org) for complete information. Applicants should email the completed application form and all other requested documents and information to the NeuroTrans office: office@neurotrans.org
Criteri di selezione in inglese (breve descrizione)	The application for admission to PhD studies shall be submitted by the deadline 22 june 2020, 12 pm (CET). Applicants should consult the webpage of NeuroTrans (www.neurotrans.org) for complete information. Applicants should email the completed application form and all other requested documents and information to the NeuroTrans office: office@neurotrans.org

 

Finanziatore

Nome dell'Ente finanziatore	Università degli Studi dell'Insubria
Tipologia dell'Ente	Academic
Paese dell'Ente	Italy
Città	Varese
Sito web	http://www,uninsubria,it

 

Contatto presso l'Ente

E-mail	scuola.dottorato@uninsubria.it

 

EU Research Framework Programme

La borsa è finanziata/cofinanziata attraverso un EU Research Framework Programme?	H2020/Marie Curie Actions (Except Cofund)

 

Dettagli per la candidatura

Data di scadenza del bando	22/06/2020
Come candidarsi	www.neurotrans.org